Pfizer has the Highest Number of Completed & Total Clinical Trials, Followed by Merck &Co and Sanofi

DUBLIN–(BUSINESS WIRE)–The “Market Spotlight: Osteoarthritis” report has been added to ResearchAndMarkets.com’s offering.

This Market Spotlight report covers the Osteoarthritis market, comprising key pipeline and marketed drugs, clinical trials, upcoming and regulatory events, patent information, a 10-year disease prevalence forecast, and licensing and acquisition deals, as well as presenting drug-specific revenue forecasts.

Key Takeaways

• The author estimates that in 2016, there were 301.6 million prevalent cases of osteoarthritis (knee or hip) in adults aged 30 years and older worldwide, and forecasts that number to increase to 352.2 million prevalent cases by 2025.
• The global prevalence of osteoarthritis is estimated to be 8.2%. Approved drugs in the osteoarthritis space focus on a wide variety of targets. The approved therapies are commonly administered via the oral route, with a few products being available in topical, intraarticular, and transdermal formulations.
• The majority of industry-sponsored drugs in active clinical development for osteoarthritis are in Phase II. Therapies in mid- and late-stage development for osteoarthritis focus on a wide variety of targets. These drugs are administered via various routes, including oral, transdermal, subcutaneous, intraarticular, intravenous, and subcutaneous administration.
• High impact upcoming events for drugs in the osteoarthritis space comprise topline Phase II and Phase III trial results, and an expected regulatory meeting with the FDA.
• There have been 41 licensing and asset acquisition deals involving osteoarthritis drugs during 2013-18. The largest deal was the $454m license agreement between Novartis and XOMA in August 2017, pursuant to which Novartis was granted a worldwide, exclusive, royalty-bearing license to XOMA’s gevokizumab program.
• The distribution of clinical trials across Phase I-IV indicates that the majority of trials for osteoarthritis have been in the early and mid-phases of development, with 57% of trials in Phase I-II, and 43% in Phase III-IV.
• The US has a substantial lead in the number of osteoarthritis clinical trials globally. The UK leads the major EU markets, while South Korea has the top spot in Asia.
• Pfizer has the highest number of completed clinical trials for osteoarthritis with 106 trials, and also leads industry sponsors with the highest number of total clinical trials for osteoarthritis, followed by Merck & Co and Sanofi.

Companies Mentioned

• Novartis
• XOMA
• Sanofi
• Merck & Co
• Mitsubishi
• Flexion
• Limited Japan

Topics Covered

OVERVIEW

KEY TAKEAWAYS

DISEASE BACKGROUND

TREATMENT

Non-pharmacological treatment

Pharmacological treatment

Surgery

EPIDEMIOLOGY

MARKETED DRUGS

Approvals by country

PIPELINE DRUGS

KEY UPCOMING EVENTS

KEY REGULATORY EVENTS

Nature Cell Keeps Hopes Up For JointStem Despite Conditional Approval Rejection

First Approval For Kolon’s Invossa But No Disease-Modifying Status

Limited Japan Nod For Cytori’s Osteoarthritis Cell Therapy

LICENSING AND ASSET ACQUISITION DEALS

Osteoarthritis Stem Cell Therapy Could Be On Sale In India By 2020

Flexion Gets Osteoarthritis Gene Therapy From GeneQuine

Mitsubishi Seeks To Revoke Kolon Gene Therapy Deal But Damage Limited?

PARENT PATENTS

REVENUE OPPORTUNITY

CLINICAL TRIAL LANDSCAPE

Sponsors by status

Sponsors by phase

Recent events

BIBLIOGRAPHY

Prescription information

APPENDIX

LIST OF FIGURES

Figure 1: Trends in prevalent cases of osteoarthritis (knee or hip), 2016-25

Figure 2: Pipeline drugs for osteoarthritis in the US

Figure 3: Pipeline drugs for osteoarthritis, by company

Figure 4: Pipeline drugs for osteoarthritis, by drug type

Figure 5: Pipeline drugs for osteoarthritis, by classifications

Figure 6: Key upcoming events in osteoarthritis

Figure 7: Licensing and asset acquisition deals in disease name, 2013-18

Figure 8: Parent patents in osteoarthritis

Figure 9: Clinical trials in osteoarthritis

Figure 10: Top 10 drugs for clinical trials in osteoarthritis

Figure 11: Top 10 companies for clinical trials in osteoarthritis

Figure 12: Trial locations in osteoarthritis

Figure 13: Osteoarthritis trial status

Figure 14: Osteoarthritis trial sponsors, by phase

LIST OF TABLES

Table 1: Prevalent cases of osteoarthritis (knee or hip), 2016-25

Table 2: Marketed drugs for osteoarthritis

Table 3: Approvals by country for osteoarthritis

Table 4: Pipeline drugs for osteoarthritis in the US

Table 5: Historical global sales, by drug ($m), 2012-17

Table 6: Forecasted global sales, by drug ($m), 2018-22

For more information about this report visit https://www.researchandmarkets.com/r/q6wr0a

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Related Topics: Musculoskeletal Disorders Drugs