February 22, 2017
Syros finds alterations in the regulatory regions of genome tumor-associated macrophages in subset of pancreatic cancer tissues
Syros scientists discovered alterations in regulatory regions of the genome in tumor-associated macrophages in a subset of patient tissues, the company said on Tuesday. Because these alterations are unique to the immunosuppressive state, they could point to genes critical for driving immunosuppression in the tumor microenvironment, as well as potential drug targets to reactivate the immune system to fight cancer.