Tag: oncology

Poolbeg doses first patient in its CRS prevention trial, but the real test is n=30
July 13, 2026 Off

Poolbeg doses first patient in its CRS prevention trial, but the real test is n=30

By Dino Mustafić

Poolbeg Pharma (AIM: POLB) said on 13 July that the first patient has been dosed in its POLB 001 TOPICAL trial, according to the company’s RNS statement, and that University College London Hospital has now also been activated as a clinical trial site, with additional sites expected to open imminently. Investor reaction will hinge less on the milestone itself — dosing a first patient is table stakes for any trial — and more on what happens over the next six to eight weeks, since interim data is still on track for late summer.

Breas and ovarian cancer newly linked to thousands of gene variants
September 18, 2024 Off

Breas and ovarian cancer newly linked to thousands of gene variants

By Dino Mustafić

Researchers from the Wellcome Sanger Institute and their collaborators focused on the ‘cancer protection’ gene RAD51C, known to increase ovarian cancer risk six-fold and risk of aggressive subtypes of breast cancer four-fold. They found over 3,000 harmful genetic changes that could potentially disrupt its function and increase cancer risk. These findings were confirmed by analysing data from large-scale health databases.   

October 19, 2023 Off By Dino Mustafić

SOPHiA genetics with with Memorial Sloan Kettering Cancer Center (MSK), a top cancer treatment and research institution, and AstraZeneca have entered a collaboration to work on providing inclusive access to comprehensive cancer testing worldwide.