Tag: Novartis

March 30, 2017 Off

FDA accepts Novartis’s BLA for acute lymphoblastic leukemia treatment

By Dino Mustafić

US Food and Drug Administration (FDA) has accepted the Novertis’s Biologics License Application (BLA) filing and granted priority review for CTL019 (tisagenlecleucel-T), an investigational chimeric antigen receptor T cell (CAR-T) therapy, in relapsed and refractory (r/r) pediatric and young adult patients with B-cell acute lymphoblastic leukemia (ALL).

March 18, 2017 Off

Novartis’ Entresto improves glycemic control in reduced ejection fraction heart failure patients with diabetes

By Dino Mustafić

New analysis shows Novartis’ Entresto improves glycemic control in reduced ejection fraction heart failure patients with diabetes. Novartis said on Saturday the new post-hoc analysis of PARADIGM-HF data demonstrates Entresto lowered levels of HbA1c (a measure of glycemic control) by 0.26% vs. 0.16% for ACE-inhibitor enalapril in heart failure with reduced ejection fraction (HFrEF) patients who also had diabetes.