Tag: CAR-Tcell

February 26, 2019 Off

Cellectis has new ways to Improve the safety of CAR T-cell therapy and prevent CRS

Cellectis developed engineered GMCSF Knock-Out CAR T-cells through TALEN-mediated gene inactivation, which found to prevent secretion of pro-inflammatory cytokines by monocytes, without compromising CAR T-cell anti-tumor activity, thebiopharmaceutical company said Tuesday in a press release.

January 23, 2017 Off

Cellestis’s scientists on safety in new CAR architecture

By Dino Mustafić

Cellectis’s scinetists lead by Dr Alexandre Juillerat have designed a new CAR architecture that contains an integrated microenvironment sensor. Their work was recently published in a scientific magazine “Scientific Reports”.