Tag: cancer

Breas and ovarian cancer newly linked to thousands of gene variants
September 18, 2024 Off

Breas and ovarian cancer newly linked to thousands of gene variants

By Dino Mustafić

Researchers from the Wellcome Sanger Institute and their collaborators focused on the ‘cancer protection’ gene RAD51C, known to increase ovarian cancer risk six-fold and risk of aggressive subtypes of breast cancer four-fold. They found over 3,000 harmful genetic changes that could potentially disrupt its function and increase cancer risk. These findings were confirmed by analysing data from large-scale health databases.   

USFDA accepts Novartis’ tislelizumab for people with esophageal cancer
September 13, 2021 Off

USFDA accepts Novartis’ tislelizumab for people with esophageal cancer

By Dino Mustafić

Novartis got an acceptance by the US Food and Drug Administration (FDA) for its Biologics License Application (BLA) for anti-PD-1 immune checkpoint inhibitor tislelizumab for the treatment of unresectable recurrent locally advanced or metastatic esophageal squamous cell carcinoma (ESCC) in people who had received prior systemic therapy.

April 30, 2020 Off

Cancer testing and diagnosis hit by sharp downturn

By BusinessWire

Diaceutics data analytics shows 31% drop in the number of newly-diagnosed patients with lung cancer, with decrease in the number of colorectal, breast and ovarian cancers patients diagnosed, and 14% drop in newly-diagnosed patients with acute myeloid leukemia

Daiichi Sankyo’s U3-1402 show reduction in tumor size in testing
September 10, 2019 Off

Daiichi Sankyo’s U3-1402 show reduction in tumor size in testing

By Dino Mustafić

Daiichi Sankyo’s test of HER3 antibody drug conjugate U3-1402 data suggest that targeting HER3 with may be an effective treatment strategy irrespective of mechanism of resistance identified in the setting of EGFR TKI resistance, where new precision treatments are needed, said Helena Yu, MD, Medical Oncologist, Memorial Sloan Kettering Cancer Center, and a trial investigator.