Systemic Hypertension Market Spotlight Report 2021: 10-Year Disease Prevalence Forecast, Clinical Trials, Regulatory Events, Licensing and Acquisitions, and Drug-specific Revenue Forecasts – ResearchAndMarkets.com

DUBLIN–(BUSINESS WIRE)–The “Market Spotlight: Systemic Hypertension” report has been added to ResearchAndMarkets.com’s offering.

This Market Spotlight report covers the Systemic Hypertension market, comprising key marketed and pipeline drugs, clinical trials, recent events and analyst opinion, upcoming and regulatory events, probability of success, a 10-year disease prevalence forecast, and licensing and acquisition deals, as well as presenting drug-specific revenue forecasts.

Key Takeaways

• The publisher estimates that in 2017, there were approximately 1.7 billion prevalent cases of systemic hypertension worldwide, and forecasts that number to increase to 1.9 billion prevalent cases by 2026.
• Systemic hypertension has a slight male predominance. Globally, the publisher estimates that in 2017, 53.31% of cases aged 25 years and over were male.
• The approved drugs in the systemic hypertension space focus on a wide variety of targets. These drugs are commonly administered via the oral route, with a few products being available in intravenous, intramuscular, and transdermal formulations.
• The largest proportion of industry-sponsored drugs in active clinical development for systemic hypertension are in Phase II. Therapies in development for systemic hypertension focus on a wide variety of targets. The majority of pipeline drugs are administered via the oral route, with the remainder being intranasal, subcutaneous, and topical formulations.
• High-impact upcoming events for drugs in the systemic hypertension space comprise topline Phase III trial results for firibastat and aprocitentan.
• The overall likelihood of approval of a Phase I systemic hypertension asset is 6.6%, and the average probability a drug advances from Phase III is 69.6%. Drugs, on average, take 7.3 years from Phase I to approval, compared to 10.1 years in the overall cardiovascular space.
• Proportions of clinical trials for hypertension across phases of development show that there has been a balance of 50% in Phase I-II and 50% in Phase III-IV.
• The US has a substantial lead in the number of hypertension clinical trials globally. Germany leads the major European markets, while South Korea has the top spot in Asia. – Clinical trial activity in the hypertension space is dominated by completed trials. Novartis has the highest number of completed clinical trials for hypertension, with 432 trials. Novartis also leads industry sponsors with by far the highest overall number of clinical trials for hypertension.

Key Topics Covered:

OVERVIEW

KEY TAKEAWAYS

DISEASE BACKGROUND

TREATMENT

• Pharmacological therapy

EPIDEMIOLOGY

MARKETED DRUGS

PIPELINE DRUGS

RECENT EVENTS AND ANALYST OPINION

• KBP-5074 for Systemic Hypertension (December 4, 2020)

KEY UPCOMING EVENTS

KEY REGULATORY EVENTS

• SoniVie, ReCor Move Forward With Ultrasound Renal Denervation Technologies

PROBABILITY OF SUCCESS

LICENSING AND ASSET ACQUISITION DEALS

• ANI Snaps Up Novitium In Deal Worth Up To $210m
• Athena Licenses Tris Technology For Hypertension Therapy
• Quantum Brings In Qilu As Greater China Partner
• Quantum Licenses Xediton Canadian Rights To Hypertension Therapy
• Quantum, Orient EuroPharma Partner On Resistant Hypertension Therapy

REVENUE OPPORTUNITY

CLINICAL TRIAL LANDSCAPE

• Sponsors by status
• Sponsors by phase

BIBLIOGRAPHY

APPENDIX

For more information about this report visit https://www.researchandmarkets.com/r/tfvxm9

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