SOPHiA GENETICS Announces Closing of $234 Million Initial Public Offering and $20 Million Private Placement

BOSTON and LAUSANNE, Switzerland, July 27, 2021 (GLOBE NEWSWIRE) — SOPHiA GENETICS SA (Nasdaq: SOPH), the creator of a global data pooling and knowledge sharing platform that advances data-driven medicine, announced today the closing of its initial public offering of 13,000,000 ordinary shares at a price of $18 per share. The gross proceeds from the offering, before deducting underwriting discounts and commissions and estimated fees and offering expenses payable by SOPHiA GENETICS SA, are $234 million. In addition, SOPHiA GENETICS SA has granted the underwriters an option to purchase up to 1,950,000 additional ordinary shares at the initial public offering price, less underwriting discounts and commissions. The ordinary shares began trading on the Nasdaq Global Select Market on July 23, 2021 under the symbol “SOPH.” In addition, SOPHiA GENETICS SA announced today the closing of a private placement, in which it issued and sold 1,111,111 ordinary shares to an affiliate of GE Healthcare. The gross proceeds from the private placement, before deducting estimated expenses payable by SOPHiA GENETICS SA, are $20 million. The sale of ordinary shares in the private placement was made pursuant to an exemption from the registration requirements of the U.S. Securities Act of 1933, as amended. J.P. Morgan, Morgan Stanley, Cowen and Credit Suisse acted as joint book-running managers for the initial public offering. A registration statement relating to the securities sold in the initial public offering has been filed with, and declared effective by, the U.S. Securities and Exchange Commission. The initial public offering was made only by means of a prospectus. Copies of the prospectus relating to the offering may be obtained from J.P. Morgan Securities LLC, c/o Broadridge Financial Solutions, 1155 Long Island Avenue, Edgewood, NY 11717, by telephone at (212) 834-4533 or by email at [email protected]; Morgan Stanley & Co. LLC, Attn: Prospectus Department, 180 Varick Street, 2nd Floor, New York, NY 10014, by telephone at (866) 718-1649 or by email at [email protected]; Cowen and Company, LLC, c/o Broadridge Financial Solutions, Attn: Prospectus Department, 1155 Long Island Avenue, Edgewood, NY 11717, by telephone at (833) 297-2926 or by email at [email protected]; and Credit Suisse Securities (USA) LLC, Attn: Prospectus Department, 6933 Louis Stephens Drive, Morrisville, NC 27560, by telephone at (800) 221-1037 or by email at [email protected]. This press release shall not constitute an offer to sell or the solicitation of an offer to buy any securities, nor shall there be any sale of any securities in any state or jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state or jurisdiction. There is no intention to publicly offer, solicit, sell or advertise, directly or indirectly, any securities, or invest in securities of SOPHiA GENETICS SA, such as the ordinary shares, in, into or from Switzerland and the securities will not be listed on the SIX Swiss Exchange or on any other exchange or regulated trading venue in Switzerland. The ordinary shares may not be publicly offered, directly or indirectly, in Switzerland within the meaning of the Swiss Financial Services Act (“FinSA”), except under an exemption from the prospectus requirements under the FinSA. No application has or will be made to admit the ordinary shares to trading on any trading venue (exchange or multilateral trading facility) in Switzerland. Neither this document nor any other offering or marketing material relating to any securities, such as the ordinary shares, constitutes or will constitute a prospectus pursuant to the FinSA, and neither this document nor any other offering or marketing material relating to the ordinary shares constitutes a prospectus pursuant to the FinSA, and neither this document nor any other offering or marketing material relating to the ordinary shares may be publicly distributed or otherwise made publicly available in Switzerland in a manner which would require the publication of a prospectus pursuant to the FinSA. About SOPHiA GENETICS SOPHiA GENETICS (Nasdaq: SOPH) is a healthcare technology company dedicated to establishing the practice of data-driven medicine as the standard of care and for life sciences research. It is the creator of the SOPHiA DDM™ Platform, a cloud-based SaaS platform capable of analyzing data and generating insights from complex multimodal data sets and different diagnostic modalities. The SOPHiA DDM™ Platform and related solutions, products and services are currently used by more than 780 hospital, laboratory and biopharma institutions globally. Media Contact:[email protected] Investor Contact:Carrie [email protected]