Global Acne Market Spotlight 2017-2018 & 2019-2026 – ResearchAndMarkets.com

June 19, 2019 Off By BusinessWire

DUBLIN–(BUSINESS WIRE)–The “Market
Spotlight: Acne”
report has been added to ResearchAndMarkets.com’s
offering.

This Market Spotlight report covers the Acne market, comprising key
pipeline and marketed drugs, clinical trials, upcoming and regulatory
events, patent information, a 10-year disease prevalence forecast, and
licensing and acquisition deals, as well as presenting drug-specific
revenue forecasts

Key Takeaways

  • The report estimates that in 2017, there were approximately 624
    million prevalent cases of acne worldwide, and forecasts that number
    to increase to 683 million prevalent cases by 2026.
  • Approved drugs in the acne space focus on a wide variety of targets.
    These drugs are commonly administered via the oral and topical routes.
  • The majority of industry-sponsored drugs in active clinical
    development for acne are in Phase II, with one drug in the NDA/BLA
    phase.
  • Therapies in mid-to-late-stage development for acne focus on a wide
    variety of targets. The majority of the pipeline drugs are
    administered via the topical route, with the remainder being oral,
    subcutaneous, intranasal, or intravenous formulations.
  • High-impact upcoming events for drugs in the acne space comprise
    topline Phase II trial results for BTX-1503 and VB 1953, topline Phase
    III trial results for Winlevi/Breezula and TWIN, and an estimated
    PDUFA date for FMX101.
  • The overall likelihood of approval of a Phase I dermatology-general
    asset is 28.0%, and the average probability a drug advances from Phase
    III is 72.4%. Drugs, on average, take 7.8 years from Phase I to
    approval in both the dermatology-general space and the overall
    dermatology space.
  • There have been 21 licensing and asset acquisition deals involving
    acne drugs during 2014-19, seven of which occurred in 2014. The
    largest deal was the $650m agreement in 2018 between Almirall and
    Allergan for the acquisition of a portfolio of five products from
    Allergan’s Medical Dermatology unit in the US, which comprises of
    mature and growth brands Aczone (dapsone), Tazorac (tazarotene),
    Azelex (azelaic acid), Cordran Tape (fludroxycortide), and Seysara
    (sarecycline).
  • The distribution of clinical trials across Phase I-IV indicates that
    the majority of trials for acne have been in the late phases of
    development, with 53% of trials in Phase III-IV, and 47% in Phase I-II.
  • The US has a substantial lead in the number of acne clinical trials
    globally. Germany leads the major EU markets, while Japan has the top
    spot in Asia.
  • Clinical trial activity in the acne space is dominated by completed
    trials. GlaxoSmithKline has the highest number of completed clinical
    trials for acne, with 35 trials.
  • GlaxoSmithKline leads industry sponsors with by far the highest number
    of clinical trials for acne, followed by Allergan

Key Topics Covered:

OVERVIEW

KEY TAKEAWAYS

DISEASE BACKGROUND

TREATMENT

Topical therapy

Systemic therapy

Physical treatments

EPIDEMIOLOGY

MARKETED DRUGS

PIPELINE DRUGS

RECENT EVENTS AND ANALYST OPINION

FMX101 for Acne (September 11, 2018)

Winlevi / Breezula for Acne (July 10, 2018)

Olumacostat Glasaretil for Acne (March 5, 2018)

Ammonia Oxidizing Bacteria for Acne (October 19, 2017)

KEY UPCOMING EVENTS

KEY REGULATORY EVENTS

Foamix Submits First Topical Minocycline For Acne

Differin Extends With Cleanser, Moisturizer, Biore Adds Foam In OTC Skin
Care

PROBABILITY OF SUCCESS

LICENSING AND ASSET ACQUISITION DEALS

PARENT PATENTS

REVENUE OPPORTUNITY

CLINICAL TRIAL LANDSCAPE

Sponsors by status

Sponsors by phase

Recent events

BIBLIOGRAPHY

Prescription information

APPENDIX

For more information about this report visit https://www.researchandmarkets.com/r/9vkn0i

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Related
Topics: Dermatology