Pharmaceuticals, Biotechnology and Life Sciences
Eli Lilly’s phase 3 double-blind study (MONARCH 2) designed to evaluate the efficacy and safety of abemaciclib, in combination with fulvestrant, in patients with advanced (locoregionally recurrent or metastatic) breast cancer has met its primary endpoint.
Arix Bioscience, the Lead Discovery Center GmbH (LDC), Max Planck Innovation GmbH (MPI), and the University of Leeds have signed agreement to develop new therapeutics for metabolic diseases based on the discoveries from these organisations.
ASIT biotech, a Belgian clinical-stage biopharmaceutical company focused on the research, development and future commercialization of immunotherapy products for the treatment of allergies, has appointed Gerd Zettlmeissl as its new Chairman of the Board, Béatrice De Vos having stood down to focus on new projects.
Array BioPharma said on Sunday it has exited the U.S. Food and Drug Administration’s (FDA) Division of Oncology Products 2 its new drug application (NDA) for binimetinib monotherapy for the treatment of NRAS-mutant melanoma, a rare, mutationally-driven subset of skin cancer.
AstraZeneca has reported results of the first large real-world evidence study of its kind evaluating the risk of hospitalisation for heart failure and death from any cause in patients with type-2 diabetes (T2D) receiving treatment with a newer class of diabetes medicines, SGLT-2 inhibitors (SGLT-2i).
AB Science pharmaceutical company, specialist in the protein kinase inhibitors (PKIs), said on Monday that it had the first successful phase 3 trial of a tyrosine kinase inhibitor in the treatment of amyotrophic lateral sclerosis (ALS).
Kiadis Pharma, a clinical stage biopharmaceutical company developing innovative T-cell immunotherapy treatments for blood cancers and inherited blood disorders, has appointment Jan Feijen as Chief Operations Officer (COO) effective from April 1, 2017.
Bayer AG and Janssen Pharmaceuticals reported results from a study called Einstein Choice on Saturday.
New analysis shows Novartis’ Entresto improves glycemic control in reduced ejection fraction heart failure patients with diabetes. Novartis said on Saturday the new post-hoc analysis of PARADIGM-HF data demonstrates Entresto lowered levels of HbA1c (a measure of glycemic control) by 0.26% vs. 0.16% for ACE-inhibitor enalapril in heart failure with reduced ejection fraction (HFrEF) patients who also had diabetes.
Nordic Nanovector ASA has begin dosing patients in its Phase 1 Betalutin study, testing a CD37 targeting antibody-radionuclide conjugate, in patients with relapsed diffuse large B-cell lymphoma (DLBCL) who are ineligible for stem cell transplantation.