Plasticell, a developer of stem cell technologies and cell-based therapies, has signed agreements with the Agency for Science, Technology and Research (A*STAR) and the Nanyang Technological University (NTU) to progress its therapeutic stem cell pipeline.
The agreements were signed separately with the two Singapore research centres encompass technology licensing, collaborative research and scientific exchange visits.
Plasticell said it would collaborate with the laboratories of Prof. Peter Dröge from School of Biological Sciences, NTU and Dr. Farid Ghadessy from A*STAR to apply proprietary genome editing technology to insert functional multi-transgene cassettes into specific loci of human stem cell lines. The engineered lines will be used by Plasticell in multiple projects focused on precisely directed stem cell differentiation, phenotypic screening for drug discovery and in next-generation immuno-oncology applications.