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Failure of malaria drug “early warning” for Africa, researchers say

Fatimata Harouna holds her two-year-old daughter Aissata Dia, as she recovers from malnutrition and Malaria, at a nutrition center run by the Spanish Non-Governmental Organization Accion contra el Hambre (Action against hunger) at Selibaby's hospital, in the Guidimakha region, Mauritania June 3, 2012. A full third of the country's population, amounting to around a million people, are at risk of suffering from malnutrition if rain doesn't fall by July, according to estimates from Accion contra el Hambre, which has been warning about the food crisis since the beginning of the year after poor rainfall in 2011. REUTERS/Susana Vera (MAURITANIA - Tags: SOCIETY POVERTY HEALTH)

Fatimata Harouna holds her two-year-old daughter Aissata Dia, as she recovers from malnutrition and Malaria, at a nutrition center run by the Spanish Non-Governmental Organization Accion contra el Hambre (Action against hunger) at Selibaby's hospital, in the Guidimakha region, Mauritania June 3, 2012. A full third of the country's population, amounting to around a million people, are at risk of suffering from malnutrition if rain doesn't fall by July, according to estimates from Accion contra el Hambre, which has been warning about the food crisis since the beginning of the year after poor rainfall in 2011. REUTERS/Susana Vera (MAURITANIA - Tags: SOCIETY POVERTY HEALTH)

By Sally Hayden

LONDON (Thomson Reuters Foundation) – A drug widely used to cure malaria has failed for the first time in patients being treated in Britain, raising questions over whether the parasite is becoming resistant to drugs, researchers said on Tuesday.

Four patients who contracted malaria in Angola, Liberia and Uganda had to seek alternative medicines after the drug they were given to combat the mosquito-borne disease failed, the London School of Hygiene and Tropical Medicine (LSHTM) said in a study.

“This is concerning and may indicate that there’s a bigger story beginning to emerge in Africa,” Colin Sutherland, a medical researcher from the LSHTM, told the Thomson Reuters Foundation.

“It may be an early warning that we need to change a few things,” he said, calling for more research into the efficacy of the Artemether-lumefantrine drug.

Sutherland said he had heard anecdotes from colleagues in Africa who had also seen resistance by parasites to the drug, saying the cases seem to be developing in different parts of the continent slowly.

Sub-Saharan Africa carries a disproportionately high share of the global malaria burden and in 2015 was home to 90 percent of malaria cases and 92 percent of malaria deaths.

While deaths from the disease have fallen dramatically in the past 15 years – since 2000 malaria deaths in Africa have dropped by 62 percent – to 429,000 in 2015, there are big gaps in progress, with the poorest countries faring the worst.

(Reporting by Sally Hayden @sallyhayd, Editing by Katie Nguyen.; Please credit the Thomson Reuters Foundation, the charitable arm of Thomson Reuters, that covers humanitarian news, women’s rights, trafficking, property rights, climate change and resilience. Visit http://news.trust.org)

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