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ENYO Pharma Announces New CFO And Provides Clinical Pipeline Update

‒ Experienced Biotechnology and Investment Banking Executive Joins Executive Team ‒

‒ EYP001 in Phase II Clinical Development for the treatment of Chronic Hepatitis B and NASH ‒

LYON, France–(BUSINESS WIRE)–ENYO Pharma, a private clinical stage biotechnology company developing innovative drug candidates, today announced the appointment of Jonathan Lieber as Chief Financial Officer. He will succeed Pascale Boissel, who is leaving the Company for personal reasons.

Jacky Vonderscher, PhD, co-founder and Chief Executive Officer, stated “I would like to thank Pascale for her many contributions to the Company. She has been a valuable member of the team and I am confident that we would not be where we are today without her leadership, and guidance. We are very pleased that she will continue to work with us for a short time to ensure a seamless transition.”

Dr. Vonderscher continued, “We are very pleased to have Jon join us as our new CFO. He is an accomplished executive with a proven track record of financial and operational leadership in the biopharmaceutical industry. His experience in building and financing biotechnology companies together with his prior investment banking experience, makes him an important addition to the executive leadership team and he will be extremely valuable as we seek to advance our product pipeline. We expect that Jon will play a critical role in our efforts to fund the growth of the company.”

Jonathan Lieber is a seasoned executive with 25 years of experience in financial and executive management at emerging growth life science companies and in investment banking. During his career he has raised more than $325 million of equity and debt in public and private securities offerings, including a $110 million IPO at Altus Pharmaceuticals, and led strategic and business development transactions including the successful sale of Xcellerex to GE Healthcare. He currently serves as a Managing Director of Danforth Advisors and most recently served as CFO of Histogenics Corporation, a publicly-traded cell therapy company developing products for the orthopedics market. He received a BS in Business Administration and Finance from Boston University and an MBA in Finance from New York University Stern School of Business.

“ENYO’s innovative technology platform has already demonstrated its ability to generate multiple proprietary compounds that may enable the treatment of unmet medical needs in a variety of therapeutic areas,” said Jonathan Lieber. “I am pleased to be joining the Company at such an exciting time and I look forward to working with the leadership team to finance and grow the business with a goal of bringing novel products, such as EYP001, to patients.”

Clinical Pipeline Update

ENYO Pharma also provided a pipeline update today with a focus on EYP001 (Vonafexor, proposed INN), the Company’s FXR agonist that is currently in Phase II clinical development in both Hepatitis B (HBV) and Nonalcoholic Steatohepatitis (NASH).

About ENYO Pharma

ENYO Pharma is a privately held, clinical stage biopharmaceutical company incorporated in January 2014 and headquartered in Lyon, France. The Company’s most advanced compound, EYP001, is a small molecule (non-Bile Acid FXR agonist) therapeutic in Phase II clinical development for the treatment of Chronic Hepatitis B and NASH. EYP001 and the Company’s discovery programs are based on a proprietary technology platform that uses a virus bio-mimetism approach to enable the rapid discovery of first-in-class drug candidates with good safety profiles. ENYO’s founders are a mix of virus-host protein interactions experts from the French Infectiology Research Center in Lyon and pharmaceutical industry executives with an impressive track record in drug development.

For more information on ENYO and EYP001, please visit http://www.enyopharma.com/.

Contacts

Investor Relations:

Tel: +33 (0)4 37 70 02 27

communication@enyopharma.com

Media Relations:

Annie-Florence Loyer, NewCap Media

+33 (0)1 44 71 00 12/ +33 (0)6 88 20 35 59

afloyer@newcap.fr

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