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Automatic Sampling in Biopharmaceutical Applications and the Measurement of CQA 2022: Minimized Risk of Human Error and Improved Quality Drives Adoption – ResearchAndMarkets.com

DUBLIN–(BUSINESS WIRE)–The “Automatic Sampling in Biopharmaceutical Applications and the Measurement of CQA: Distribution by Type of Monitoring Method, Bioprocessing Method, Working Volume, Scalability, Key Geographical Regions : Industry Trends and Global Forecasts, 2022-2035” report has been added to ResearchAndMarkets.com’s offering.

The report features an extensive study on the current and future potential of automatic sampling systems.

During each stage of biopharmaceutical manufacturing process, it is essential to ensure that the bioprocess variables and parameters are under control. Sampling is considered to be an important step in the bioprocess. However, there are several challenges associated with conventional, manual aseptic sampling technique, such as high risk of contamination of the sample, high labor costs, operator-to-operator deviations during sampling and sample preparation, lower sample frequency rates and no real-time availability of data.

This has created a demand for systems that allow aseptic sampling and handling of samples, reduce errors, and increase reproducibility. As a result, automatic sampling systems have emerged to be the most appropriate solution as these systems have the potential to address a number of challenges associated with manual sampling method and offer various additional benefits including real-time data monitoring, reduction in deviations by around 65% and increase in the overall productivity up to 80%.

Moreover, automated sampling systems ensure that the processes continue to run within precise limits and make the necessary adjustments, while minimizing the risk of human errors, improving the overall product quality, timely monitoring critical process parameters, bringing tangible cost benefits and increased throughput.

Several companies are actively engaged in the manufacturing of automatic sampling systems and automatic sample preparation systems that can be used across various scale of operations in biopharmaceutical manufacturing. These systems have diverse applications, including bioprocess / analyte monitoring, fraction collection, data management and advanced process control / feedback control in biotechnology, pharmaceutical, chemical, food and cosmetic industries. In addition, automatic sampling systems use process analytical technology (PAT) that can be easily integrated in the bioprocessing unit in order to improve scalability.

Further, the field has witnessed several innovations, constantly evolving guidelines for pharmaceutical bioprocessing, mainly based on automation, digitalization and process transparency. It is also important to highlight that several equipment manufacturers offering user-friendly, controlled, and automated systems, have recently emerged.

Given the rising interest of stakeholders towards technological advancements and adoption of these systems, we believe that the overall market for automatic sampling in biopharmaceutical applications and the measurement of CQA is anticipated to witness substantial growth in the coming years.

Scope of the Report

Key Questions Answered

Key Topics Covered:

1. PREFACE

2. EXECUTIVE SUMMARY

3. INTRODUCTION

3.1. Chapter Overview

3.2. Process Analytical Technology in Sampling

3.3. Manual Sampling versus Automatic Sampling

3.4. Need for Automatic Sampling Systems

3.5. Automatic Aseptic Sampling System

3.6. Components of a Sampling System

3.7. Stand-alone Systems versus Integrated Systems

3.8. Bioprocess Monitoring and Control Methods

3.8.1. At-line Monitoring

3.8.2. In-line Monitoring

3.8.3. Off-line Monitoring

3.8.4. On-line Monitoring

3.9. Key Considerations for Automatic Sampling

3.9.1. Sample Volume

3.9.2. Cell Removal

3.9.3. Sampling Rate

3.9.4. Integration of Analyzers

3.9.5. Feedback to Bioreactor

3.9.6. Flexibility

3.9.7. Transferability

3.9.8. Price

3.10. Benefits of Automatic Sampling Systems

3.11. Standards and Requirements

3.12. Future Innovations

4. MARKET LANDSCAPE: AUTOMATIC SAMPLING SYSTEMS

5. COMPANY COMPETITIVENESS ANALYSIS

6. COMPANY PROFILES: AUTOMATIC SAMPLING SYSTEM MANUFACTURERS

6.1. Chapter Overview

6.2. Agilent Technologies

6.3. Cytiva

6.4. Mettler Toledo

6.5. Pall Corporation

6.6. Shimadzu

6.7. Xylem

7. MARKET LANDSCAPE: AUTOMATIC SAMPLE COLLECTION / PREPARATION SYSTEMS

8. COMPANY PROFILES: AUTOMATIC SAMPLE COLLECTION / PREPARATION SYSTEM MANUFACTURERS

8.1. Chapter Overview

8.2. Agilent Technologies

8.3. Biotage

8.4. Flownamics

8.5. MGI Tech

8.6. SOTAX

9. PATENT ANALYSIS

10. RECENT DEVELOPMENTS

11. SWOT ANALYSIS

12. PORTERS FIVE FORCES ANALYSIS

13. MARKET FORECAST AND OPPORTUNITY ANALYSIS

14. INDUSTRIAL REVOLUTION FROM INDUSTRY 1.0 TO INDUSTRY 5.0

15. CONCLUDING REMARKS

16. EXECUTIVE INSIGHTS

17. APPENDIX 1: TABULATED DATA

18. APPENDIX 2: LIST OF COMPANIES AND ORGANIZATIONS

For more information about this report visit https://www.researchandmarkets.com/r/ixqpkt

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